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The development of reflective thought for the training in integral people

Martínez Lozano, José Joaquín; Paz Montes, Luisa Stella; Vergel Ortega, Mawency (Logos Ciencia & Tecnología, 2018-07-01)

In this article we present results of research whose objective was to analyze experiences in the growth of plants such as the Duranta and Salvia where the student develops competences in posing and solving problems that ...
The development of reflective thought for the training in integral people

Martínez Lozano, José Joaquín; Paz Montes, Luisa Stella; Vergel Ortega, Mawency (Logos Ciencia & TecnologíaBogota , Colombia, 2018-07-01)

In this article we present results of research whose objective was to analyze experiences in the growth of plants such as the Duranta and Salvia where the student develops competences in posing and solving problems ...
Sobre el modelado matemático de la red bioquímica que describe la interacción molecular entre receptores celulares de células dentríticas y el ligando manosa de mycobacterium tuberculosis

Ibarguen, Eduardo; Burbano-Rosero, Edith Mariela; Vergel Ortega, Mawency (Revista Boletin RedipeBogota , Colombia, 2021-02-01)

A nivel mundial se considera a la tuberculosis (TB) como una enfermedad de gran importancia en la salud pública con grandes impactos socioeconómicos, presentando elevadas tasas de incidencia y mortalidad. El modelamiento ...

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The development of reflective thought for the training in integral people
...
Martínez Lozano, José Joaquín | 2018-07-01

In this article we present results of research whose objective was to analyze experiences in the growth of plants such as the Duranta and Salvia where the student develops competences in posing and solving problems that allowed him to argue, model, communicate on mathematics in improvement of their academic performance. The methodology followed a quantitative approach, field-type experimental design, applied to a sample of 180 students of engineering programs. Results: 95% of the students remained in the course, 99% scored above the general institutional average in integral calculus. Conclusion: Application in plant growth allowed to develop competences in raising and solving problems, development of mathematical thinking, analyzing variables and changes in a time, modeling situations; argue, represent entities. The use of blogs allowed the generation of new methods of study, and different forms of evaluation and evaluation of learning, both for students and teachers.

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The development of reflective thought for the training in integral people
...
Martínez Lozano, José Joaquín | 2018-07-01

In this article we present results of research whose objective was to analyze experiences in the growth of plants such as the Duranta and Salvia where the student develops competences in posing and solving problems that allowed him to argue, model, communicate on mathematics in improvement of their academic performance. The methodology followed a quantitative approach, field-type experimental design, applied to a sample of 180 students of engineering programs. Results: 95% of the students remained in the course, 99% scored above the general institutional average in integral calculus. Conclusion: Application in plant growth allowed to develop competences in raising and solving problems, development of mathematical thinking, analyzing variables and changes in a time, modeling situations; argue, represent entities. The use of blogs allowed the generation of new methods of study, and different forms of evaluation and evaluation of learning, both for students and teachers.

LEER
Sobre el modelado matemático de la red bioquímica que describe la interacción molecular entre receptores celulares de células dentríticas y el ligando manosa de mycobacterium tuberculosis
...
Ibarguen, Eduardo | 2021-02-01

A nivel mundial se considera a la tuberculosis (TB) como una enfermedad de gran importancia en la salud pública con grandes impactos socioeconómicos, presentando elevadas tasas de incidencia y mortalidad. El modelamiento matemático en el complejo CD-Mtb (Células dentríticas-Mycobacterium tuberculosis) ha sido poco estudiado, lo que representa un problema de investigación que se puede abordar con los avances actuales sobre el modelamiento en escalas moleculares, siendo "el modelo receptor-ligando con representación de estados" el más recomendado para abordar esta dinámica. Adicionalmente, la importancia de estudios en este campo radica en la predicción que permitiría efectuar la modelación en asociación al desarrollo de un estadio de Tb activa o latente. Teniendo en cuenta lo anterior, en esta investigación se enfocó en determinar los principales receptores que se acoplan con el ligando manosa en el proceso molecular de reconocimiento, además de formular a partir de la literatura disponible, una red bioquímica que acople la interacción molecular entre las células dendríticas y el patógeno Mtb en las vías de señalización que implican el reconocimiento de la manosa por los receptores de células dendríticas (DC-SIGN, TLR4, de TLR9, TLR2, MR, Dectin-2, Mincle, FcRy, Dectin-1, SIGNR-3, CR3, SR, Langerin). Se espera que a partir de esta red se desarrollen modelos matemáticos mediante sistemas de ecuaciones diferenciales, esta modelación permitirá manipular variables y parámetros, con el propósito de contestar preguntas acerca de las posibles interacciones mediadas entre doce receptores celulares y el ligando manosa.

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