Listar por autor "Barajas Solano, Andrés F."

: This study evaluated the role of C/N/P in the increase in the synthesis of carbohydrates, proteins, and lipids in two high-mountain strains of algae (Chlorella sp. UFPS019 and Desmodesmus sp. UFPS021). Three carbon ...

: Influenza is a respiratory disease that may cause severe consequences to human health. Influenza caused between 99,000 and 200,000 deaths worldwide in 2019. Studies have reported the presence of this virus in Santander, ...

Enhancement of Metabolite Production in High-Altitude Microalgal Strains by Optimized C/N/P Ratio
...
Suárez Quintana, William H. | 2022-07-04

: This study evaluated the role of C/N/P in the increase in the synthesis of carbohydrates, proteins, and lipids in two high-mountain strains of algae (Chlorella sp. UFPS019 and Desmodesmus sp. UFPS021). Three carbon sources (sodium acetate, sodium carbonate, and sodium bicarbonate), and the sources of nitrogen (NaNO3 ) and phosphate (KH2PO4 and K2HPO4 ) were analyzed using a surface response (3 factors, 2 levels). In Chlorella sp. UFPS019, the optimal conditions to enhance the synthesis of carbohydrates were high sodium carbonate content (3.53 g/L), high KH2PO4 and K2HPO4 content (0.06 and 0.14 g/L, respectively), and medium-high NaNO3 (0.1875 g/L). In the case of lipids, a high concentration of sodium acetate (1.19 g/L) coupled with high KH2PO4 and K2HPO4 content (0.056 and 0.131 g/L, respectively) and a low concentration of NaNO3 (0.075 g/L) drastically induced the synthesis of lipids. In the case of Desmodesmus sp. UFPS021, the protein content was increased using high sodium acetate (2 g/L), high KH2PO4 and K2HPO4 content (0.056 and 0.131 g/L, respectively), and high NaNO3 concentration (0.25 g/L). These results demonstrate that the correct adjustment of the C/N/P ratio can enhance the capacity of high-mountain strains of algae to produce high concentrations of carbohydrates, proteins, and lipids.

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Inherent Safety Analysis and Sustainability Evaluation of a Vaccine Production Topology in North-East Colombia
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González Delgado, Ángel Darío | 2022-08-12

: Influenza is a respiratory disease that may cause severe consequences to human health. Influenza caused between 99,000 and 200,000 deaths worldwide in 2019. Studies have reported the presence of this virus in Santander, Colombia, a region with a high humanitarian flow. An influenza vaccine production plant topology has been proposed previously. Nevertheless, the inherent safety and sustainably behavior of this topology is unknown. Process safety plays a crucial role in the evaluation of emerging technologies since it allows the identification of potential risks. Moreover, the current sustainability policies enforce the assessment of processes considering economic, social, and environmental aspects. For this reason, a safety and sustainability evaluation of a vaccine production topology is performed in this work. The inherent safety index (ISI) methodology was implemented to analyze the process. The sustainability evaluation was performed using the sustainability weighted return on investment metric (SWROIM), in which return on investment (ROI), output potential environmental impact (PEI output), total safety inherent index (ITI), and exergy efficiency were considered. The results showed that influenza vaccine production is inherently safe since the total inherent safety index was 11. The destroyed exergy was 378.69 MJ/h, the return on investment was 86%, and the SWROIM was estimated at 81%, which means slightly negative impacts on sustainability

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Listar por autor "Barajas Solano, Andrés F."

Enhancement of Metabolite Production in High-Altitude Microalgal Strains by Optimized C/N/P Ratio

Inherent Safety Analysis and Sustainability Evaluation of a Vaccine Production Topology in North-East Colombia

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Enhancement of Metabolite Production in High-Altitude Microalgal Strains by Optimized C/N/P Ratio

Inherent Safety Analysis and Sustainability Evaluation of a Vaccine Production Topology in North-East Colombia

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Listar por autor "Barajas Solano, Andrés F."

Enhancement of Metabolite Production in High-Altitude Microalgal Strains by Optimized C/N/P Ratio ﻿

Inherent Safety Analysis and Sustainability Evaluation of a Vaccine Production Topology in North-East Colombia ﻿

Envíos recientes

Enhancement of Metabolite Production in High-Altitude Microalgal Strains by Optimized C/N/P Ratio

Inherent Safety Analysis and Sustainability Evaluation of a Vaccine Production Topology in North-East Colombia

Portales Institucionales

Enhancement of Metabolite Production in High-Altitude Microalgal Strains by Optimized C/N/P Ratio

Inherent Safety Analysis and Sustainability Evaluation of a Vaccine Production Topology in North-East Colombia