TY - NEWS
TI - Inherent Safety Analysis and Sustainability Evaluation of a Vaccine Production Topology in North-East Colombia
AU - González Delgado, Ángel Darío
AU - García Martínez, Janet B.
AU - Barajas Solano, Andrés F.
AB - : Influenza is a respiratory disease that may cause severe consequences to human health.
Influenza caused between 99,000 and 200,000 deaths worldwide in 2019. Studies have reported the
presence of this virus in Santander, Colombia, a region with a high humanitarian flow. An influenza
vaccine production plant topology has been proposed previously. Nevertheless, the inherent safety
and sustainably behavior of this topology is unknown. Process safety plays a crucial role in the
evaluation of emerging technologies since it allows the identification of potential risks. Moreover, the
current sustainability policies enforce the assessment of processes considering economic, social, and
environmental aspects. For this reason, a safety and sustainability evaluation of a vaccine production
topology is performed in this work. The inherent safety index (ISI) methodology was implemented to
analyze the process. The sustainability evaluation was performed using the sustainability weighted
return on investment metric (SWROIM), in which return on investment (ROI), output potential
environmental impact (PEI output), total safety inherent index (ITI), and exergy efficiency were
considered. The results showed that influenza vaccine production is inherently safe since the total
inherent safety index was 11. The destroyed exergy was 378.69 MJ/h, the return on investment was
86%, and the SWROIM was estimated at 81%, which means slightly negative impacts on sustainability
DA - 2022-08-12
KW - sustainability indicators
KW - SWROIM;
KW - total inherent safety index
KW - exergy efficiency
KW - influenza vaccine
KW - ROI
KW - potential environmental impacts
PB - Sustainability
UR - https://repositorio.ufps.edu.co/handle/ufps/6527
ER -