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dc.contributor.authorRivera, Christian
dc.contributor.authorGelves, German
dc.contributor.authorNieto, Luis M.
dc.date.accessioned2021-10-25T20:54:39Z
dc.date.available2021-10-25T20:54:39Z
dc.date.issued2020-09-13
dc.identifier.urihttp://repositorio.ufps.edu.co/handle/ufps/410
dc.description.abstractItaconic acid is a metabolite produced from biotechnological pathway using the microorganism Aspergillus terreus. It is used in a wide number of sectors such as industry, agriculture and health. Based on its chemical properties, itaconic acid is a great interest for replacing polymers and resins derived from petroleum. However, its production is still expensive and this latter hinders large scale studies regarding itaconic acid production. Nowadays, simulation is a great alternative to overcome this problem. It allows researchers to make a more effective evaluation and self-assessment, reducing costs and avoiding losses at large scale operation. For that reason, the purpose of this research is performing an Itaconic acid production simulation on industrial scale using SuperPro Designer software. Costs reduction improvement is also analyzed. 90g/L of glycerol, 1g/L of NH4NO3 and 1.25 of KH2PO4 are set up on simulation as media composition reported from references. Results regarding itaconic acid crystals showed a productivity of 171 kg/h and an operating cost closed to 42.0 USD/kg. Interestingly, a 17 % productivity increase is reached by proposing a stream recycling based on itaconic acid recovering from downstream centrifugation processing. The latter based on a higher productivity estimated (200 kg/h). Also average costs are reduced at 12 % since 38.1 USD/kg is found using improvements mentioned. Results found here demonstrate the potential usage of simulators for estimating costs and production which allows predicting the bioprocess feasibilityeng
dc.format.extent12 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherJournal of Physicsspa
dc.relation.ispartofJournal of Physics: Conference Series ISSN: 1742-6596, 2020 vol:1655 fasc: N/A págs: 1 - 12, DOI:10.1088/1742-6596/1655/1/012100
dc.rightsContent from this work may be used under the terms of theCreative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Published under licence by IOP Publishing Ltdeng
dc.sourcehttps://iopscience.iop.org/article/10.1088/1742-6596/1655/1/012100spa
dc.titleEconomic Assessment of Itaconic Acid Production from Aspergillus Terreus using Superpro Designereng
dc.typeArtículo de revistaspa
dcterms.referencesJing Y, Hao X, Jianchun J, Ning Z, Xie J, Wei M and Zhao J 2019 Production of Itaconic Acid Through Microbiological Fermentation of Inexpensive Materials Journal of Bioresources and Bioproducts 4(3) 135spa
dcterms.referencesCunha J, Machado A and Camporese E 2018 World market and biotechnological production of itaconic acid Biotechnology 8(3) 1spa
dcterms.referencesBafana R, Sivanesan S and Pandey R 2019 Optimization and scale up of itaconic acid production from potato starch waste in stirred tank bioreactor Biotechnology Progress 35(3) 2774spa
dcterms.referencesSteiger M, Blumhoff M, Mattanovich D and Sauer M 2013 Biochemistry of microbial itaconic acid production Frontiers in Microbiology 4 1spa
dcterms.referencesCruz J, Bernardes D, Machado A and Camporese E 2017 Itaconic acid production by Aspergillus terreus from low-cost carbon and nitrogen sources International Journal of Engineering and Technical Research 7(9) 32spa
dcterms.referencesBednarz S, Półćwiartek K, Wityk J, Strachota B, Kredatusová J, Beneš H, Wesolowska A and Kowalski G 2017 Polymerization-crosslinking of renewable itaconic acid in water and in deep eutectic solvents European Polymer Journal 95 241spa
dcterms.referencesBafana R, Sivanesan S and Pandey R 2017 Itaconic Acid Production by Filamentous Fungi in Starch-Rich Industrial Residues Indian Journal of Microbiology 57(3) 322spa
dcterms.referencesKlement T and Büchs J 2013 Itaconic acid – a biotechnological process in change, Bioresources Technology 135 422spa
dcterms.referencesSaha B and Kennedy G 2019 Efficient itaconic acid production by Aspergillus terreus: Overcoming the strong inhibitory effect of manganese Biotechnology Progress 36 2939spa
dcterms.referencesPetrides D, Carmichael D, Charles C and Koulouris A 2014 Biopharmaceutical Process Optimization with Simulation and Scheduling Tools Bioengineering Journal 1 54spa
dcterms.referencesJuy M, Orejas J and Lucca M 2014 Study of itaconic acid production by Aspergillus terrus MJL05 strain with different variable Revista Colombiana de Biotecnologia 12(2) 187spa
dcterms.referencesAmina I and Chenyu D 2014 Fermentative Itaconic Acid Production Journal of Biodiversity Bioprospecting and Development 1(2)spa
dcterms.referencesMagalhães J, Carvalho J, Thoms J, Coral D and Soccol C 2018 Techno-economic Analysis of Downstream Processes in Itaconic Acid Production from Fermentation Broth. Journal of Cleaner Production 206(1) 336spa
dcterms.referencesMagalhães I, Carvalho J, Medina J and Soccol C 2016 Downstream process development in biotechnological itaconic acid manufacturing Applied Microbiology and Biotechnology 101(1) 1spa
dc.identifier.doi10.1088/1742-6596/1655/1/012100
dc.publisher.placeReino Unidospa
dc.relation.citationeditionVol. 1655,No. 1(2020)spa
dc.relation.citationendpage12spa
dc.relation.citationissue1 (2020)spa
dc.relation.citationstartpage1spa
dc.relation.citationvolume1655spa
dc.relation.citesL Nieto et al 2020 J. Phys.: Conf. Ser. 1655 012100
dc.relation.ispartofjournalJournal of Physicsspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución 4.0 Internacional (CC BY 4.0)spa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa


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