| dc.contributor.author | Galvis, Fabian | |
| dc.contributor.author | Moreno Rozo, laura Yolima | |
| dc.date.accessioned | 2021-12-09T20:41:04Z | |
| dc.date.available | 2021-12-09T20:41:04Z | |
| dc.date.issued | 2019-06 | |
| dc.identifier.uri | http://repositorio.ufps.edu.co/handle/ufps/1781 | |
| dc.description.abstract | Background: The expression of CTX-M β-lactamases belonging to groups 1 and 9 in Klebsiella pneumoniae
produces high levels of resistance to ceftazidime, and they have a wide distribution worldwide. Aim: To identify
and characterize the blaCTX-M-Group1 and blaCTX-M-Group9 genes in K. pneumoniae isolates resistant to ceftazidime
in a hospital in San José de Cúcuta, Colombia. Material and Methods: Primers were designed for the identification
of K. pneumoniae and blaCTX-M genes by PCR. Subsequently, the genetic relationship of these isolates was analyzed
by REP-PCR. Results: A 38% of the 24 isolates identified by PCR as K. pneumoniae showed blaCTX-M-3. blaCTX-M-15
y blaCTX-M-32 genes (Group CTX-M-1) and 42% blaCTX-M14. blaCTX-M-24 y blaCTX-M-27 genes (Group CTX-M-9). The
phylogenetic analysis grouped the K. pneumoniae isolates into 4 clusters, showing correlation in clusters I, II
and IV, when comparing the genetic profiles with the type of sample and group of genes. Discussion: We found
a similar frequency of blaCTX-M-Group 1 and blaCTX-M-Group 9 genes in isolates of K. pneumoniae resistant to
ceftazidime. The correlation between the REP-PCR with the CTX-M groups and the type of sample revealed the
presence of three clonal pattern | eng |
| dc.format.mimetype | application/pdf | spa |
| dc.language.iso | eng | spa |
| dc.publisher | Revista Chilena de Infectologia | spa |
| dc.relation.ispartof | Revista chilena de infectología | |
| dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited | eng |
| dc.source | https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182019000300304&lng=en&nrm=iso&tlng=en | spa |
| dc.title | Caracterización molecular y detección de genes blaCTX-M grupos 1 y 9 en Klebsiella pneumoniae resistentes a ceftazidima, en un hospital de San José de Cúcuta, Colombia | eng |
| dc.type | Artículo de revista | spa |
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| dc.coverage.city | San Jose De Cùcuta , Colombia | |
| dc.identifier.doi | http://dx.doi.org/10.4067/S0716-10182019000300304 | |
| dc.publisher.place | Santiago de Chile , Chile | spa |
| dc.relation.citationedition | Vol.36 No.3.(2019) | spa |
| dc.relation.citationendpage | 311 | spa |
| dc.relation.citationissue | 3 (2019) | spa |
| dc.relation.citationstartpage | 304 | spa |
| dc.relation.citationvolume | 36 | spa |
| dc.relation.cites | Galvis, F., & Moreno, L. (2019). Caracterización molecular y detección de genes blaCTX-M grupos 1 y 9 en Klebsiella pneumoniae resistentes a ceftazidima, en un hospital de San José de Cúcuta, Colombia. Revista chilena de infectología, 36(3), 304-311. | |
| dc.relation.ispartofjournal | Molecular characterization and detection of genes blaCTX-M groups 1 and 9 in Klebsiella pneumoniae resistant to ceftazidime, in a hospital in San José de Cúcuta, Colombia | spa |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.creativecommons | Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) | spa |
| dc.subject.proposal | blaCTX-M | spa |
| dc.subject.proposal | ceftazidima | spa |
| dc.subject.proposal | Klebsiella pneumoniae | eng |
| dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
| dc.type.content | Text | spa |
| dc.type.driver | info:eu-repo/semantics/article | spa |
| dc.type.redcol | http://purl.org/redcol/resource_type/ART | spa |
| oaire.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
| dc.type.version | info:eu-repo/semantics/publishedVersion | spa |
