TY - NEWS
TI - Non-Newtonian Behavior Effect on Gas-liquid Mass Transfer using an Anchor Impeller for CSTR Bioreactors: A CFD Approach
AU - Niño, Lilibeth
AU - Gelves, German
AU - Peñuela, Mariana
AB - Objectives: kL a mass transfer coefficient was predicted using CFD (computational fluid dynamics) for analyzing non-newtonian effects on gas liquid mass transfer in a 10 L bioreactor stirred with an Anchor Impeller. Methods/Statistical Analysis: The set up bioreactor configurations were defined by typical culturing conditions used for fungi organism. Bubble breakage frequency and coalescence rate were simulated using Luo - Colaloglou and Tavlarides models and PBM approaches, respectively. Simulated results from different shear rates due to non-newtonian behaviour are compared by analyzing its influences in bubble size and power input. Findings: A clear relationship between high levels of shear rates and small bubble sizes is found in this work. The later is also associated with the high values of kL a simulated (270 h-1) and compared to levels found at low shear rates (62 h-1). Application/Improvements: Impressed by these findings new design optimizations for non-newtonian bioprocessing applications would be improved using CFD.
DA - 2018-11
KW - Anchor
KW - Bubble Coalescence
KW - Non-Newtonian
KW - Sauter Diameter
KW - CFD
PB - Indian Journal of Science and Technology
UR - https://repositorio.ufps.edu.co/handle/ufps/540
ER -