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dc.contributor.authorSALAZAR MERCADO, SEIR ANTONIO
dc.contributor.authorVEGA GALVIS, DIANA GABRIELA
dc.date.accessioned2024-04-05T13:39:58Z
dc.date.available2024-04-05T13:39:58Z
dc.date.issued2023-03-18
dc.identifier.urihttps://repositorio.ufps.edu.co/handle/ufps/6823
dc.description.abstractParacetamol is one of the most widely used drugs worldwide, yet its environmental presence and hazardous impact on nontarget organisms could rapidly increase. In this study, the possible cytotoxic efects of paracetamol were evaluated using two bioindicator plants Lens culinaris and Pisum sativum. Concentrations of 500, 400, 300, 200, 100, 50, 25, 5, 1 mg L−1, and a control (distilled water) were used for a total of 10 treatments, which were subsequently applied on seeds of Lens culinaris Med. and Pisum sativum L.; after 72 h of exposure, root growth, mitotic index, percentage of chromosomal abnormalities, and the presence of micronucleus were evaluated. The cytotoxic efect of paracetamol on L. culinaris and P. sativum was demonstrated, reporting the inhibition of root growth, the presence of abnormalities, and a signifcant micronucleus index at all concentrations used, which shows that this drug has a high degree of toxicity.eng
dc.format.extent12 Páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherEnvironmental Science and Pollution Researchspa
dc.relation.ispartofMercado, SAS, Galvis, DGV Bioensayo ecotoxicológico de paracetamol utilizando los bioindicadores Lens culinaris Med. y Pisum sativum L. Environ Sci Pollut Res 30 , 61965–61976 (2023). https://doi.org/10.1007/s11356-023-26475-7
dc.rightsEsta bajo una licencia CC BY (licencia Creative Commons Attribution 4.0 International)eng
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/spa
dc.sourcehttps://link.springer.com/article/10.1007/s11356-023-26475-7#article-infospa
dc.titleParacetamol ecotoxicological bioassay using the bioindicators Lens culinaris Med. and Pisum sativum Leng
dc.typeArtículo de revistaspa
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dc.identifier.doi10.1007/s11356-023-26475-7
dc.relation.citationeditionVol.30 (2023)spa
dc.relation.citationendpage61976spa
dc.relation.citationissue(2023)spa
dc.relation.citationstartpage61965spa
dc.relation.citationvolume30spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución 4.0 Internacional (CC BY 4.0)spa
dc.subject.proposalBinucleate celleng
dc.subject.proposalCell abnormalitieseng
dc.subject.proposalPharmacological compoundseng
dc.subject.proposalMitotic inhibitioneng
dc.subject.proposalMicronucleieng
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa


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