@ARTICLE{Niñ_Gas_2018,
author = "Niño, Lilibeth - Peñuela, Mariana - Gelves, German",
title = "Gas-Liquid Hydrodynamics Simulation using CFD in a Helical Ribbon Impeller Applied for Non-Newtonian Fluids",
abstract = "In the present study Computational Fluid Dynamics applied to
non-newtonian fluids was developed in order to characterize
the gas-liquid mass transfer in a 10 L bioreactor equipped
with a helical ribbon impeller. Gas-liquid Hydrodynamics was
estimated Based on CFD results. The operating conditions
chosen were defined by typical settings used for culturing
fungi organism. Turbulence, rotating flow, bubbles breakage
and coalescence were simulated by using the k-e, MRF
(Multiple Reference Frame) and PBM approaches,
respectively. The numerical results from different operational
conditions are compared by evaluating its effect on KLa.
Interested by these simulated results CFD simulations are
qualified as a very promising tool not only for predicting gasliquid hydrodynamics but also for finding design requirements
that must be implemented to optimize an aerobic
bioprocessing useful for non-newtonian applications which
are characterized by the constrain of achieving relatively high
stirring conditions and avoiding cellular damage due to
hydrodynamic conditions.",
year = 2018,
publisher = "International Journal of Applied Engineering Research",
url = "https://repositorio.ufps.edu.co/handle/ufps/1591",
}